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Prevalence of colorectal cancer biomarkers and their impact on clinical outcomes in Riyadh, Saudi Arabia

OBJECTIVES: KRAS, NRAS, and BRAF mutations are commonly present in colorectal cancer (CRC). We estimated the frequency of KRAS, NRAS, and BRAF mutations and assessed their impact on survival and other clinical variables among Saudi patients. DESIGN: Retrospective cohort study design. SETTINGS: Oncol...

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Detalles Bibliográficos
Autores principales: Alharbi, Amjad, Bin Dokhi, Haifa, Almuhaini, Ghadir, Alomran, Futoon, Masuadi, Emad, Alomran, Nouf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116043/
https://www.ncbi.nlm.nih.gov/pubmed/33979337
http://dx.doi.org/10.1371/journal.pone.0249590