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HP1 drives de novo 3D genome reorganization in early Drosophila embryos

Fundamental features of 3D genome organization are established de novo in the early embryo, including clustering of pericentromeric regions, the folding of chromosome arms and the segregation of chromosomes into active (A-) and inactive (B-) compartments. However, the molecular mechanisms that drive...

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Detalles Bibliográficos
Autores principales: Zenk, Fides, Zhan, Yinxiu, Kos, Pavel, Löser, Eva, Atinbayeva, Nazerke, Schächtle, Melanie, Tiana, Guido, Giorgetti, Luca, Iovino, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116211/
https://www.ncbi.nlm.nih.gov/pubmed/33854237
http://dx.doi.org/10.1038/s41586-021-03460-z