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Dicarbonyl stress, protein glycation and the unfolded protein response

The reactive dicarbonyl metabolite, methylglyoxal (MG), is increased in obesity and diabetes and is implicated in the development of insulin resistance, type 2 diabetes mellitus and vascular complications of diabetes. Dicarbonyl stress is the metabolic state of abnormal high MG concentration. MG is...

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Detalles Bibliográficos
Autores principales: Rabbani, Naila, Xue, Mingzhan, Thornalley, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116241/
https://www.ncbi.nlm.nih.gov/pubmed/33644826
http://dx.doi.org/10.1007/s10719-021-09980-0