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Optogenetic activation of local colonic sympathetic innervations attenuates colitis by limiting immune cell extravasation

The sympathetic nervous system is composed of an endocrine arm, regulating blood adrenaline and noradrenaline, and a local arm, a network of fibers innervating immune organs. Here, we investigated the impact of the local arm of the SNS in an inflammatory response in the colon. Intra-rectal insertion...

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Detalles Bibliográficos
Autores principales: Schiller, Maya, Azulay-Debby, Hilla, Boshnak, Nadia, Elyahu, Yehezqel, Korin, Ben, Ben-Shaanan, Tamar L., Koren, Tamar, Krot, Maria, Hakim, Fahed, Rolls, Asya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116309/
https://www.ncbi.nlm.nih.gov/pubmed/33932356
http://dx.doi.org/10.1016/j.immuni.2021.04.007