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Optogenetic activation of local colonic sympathetic innervations attenuates colitis by limiting immune cell extravasation
The sympathetic nervous system is composed of an endocrine arm, regulating blood adrenaline and noradrenaline, and a local arm, a network of fibers innervating immune organs. Here, we investigated the impact of the local arm of the SNS in an inflammatory response in the colon. Intra-rectal insertion...
Autores principales: | Schiller, Maya, Azulay-Debby, Hilla, Boshnak, Nadia, Elyahu, Yehezqel, Korin, Ben, Ben-Shaanan, Tamar L., Koren, Tamar, Krot, Maria, Hakim, Fahed, Rolls, Asya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116309/ https://www.ncbi.nlm.nih.gov/pubmed/33932356 http://dx.doi.org/10.1016/j.immuni.2021.04.007 |
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