The Dysregulation of OGT/OGA Cycle Mediates Tau and APP Neuropathology in Down Syndrome

Protein O-GlcNAcylation is a nutrient-related post-translational modification that, since its discovery some 30 years ago, has been associated with the development of neurodegenerative diseases. As reported in Alzheimer’s disease (AD), flaws in the cerebral glucose uptake translate into reduced hexo...

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Detalles Bibliográficos
Autores principales: Zuliani, Ilaria, Lanzillotta, Chiara, Tramutola, Antonella, Francioso, Antonio, Pagnotta, Sara, Barone, Eugenio, Perluigi, Marzia, Di Domenico, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116370/
https://www.ncbi.nlm.nih.gov/pubmed/33258073
http://dx.doi.org/10.1007/s13311-020-00978-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116370/
https://www.ncbi.nlm.nih.gov/pubmed/33258073
http://dx.doi.org/10.1007/s13311-020-00978-4

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