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Pharmacokinetics of Levornidazole Tablet in Healthy Chinese Subjects and Proposed Dosing Regimen Based on Pharmacokinetic/Pharmacodynamic Analysis

INTRODUCTION: Levornidazole is a novel nitroimidazole antimicrobial agent active against anaerobes. We aimed to investigate the pharmacokinetic (PK) profile of levornidazole after single and multiple oral doses of levornidazole tablets in healthy Chinese subjects and propose the dosing regimen based...

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Detalles Bibliográficos
Autores principales: Wu, Hailan, Wang, Zhiqiang, Wang, Yu, Yu, Jicheng, Fan, Yaxin, Li, Yi, Wang, Jingjing, Cao, Guoying, Guo, Beining, Chen, Yuancheng, Liu, Xiaofen, Bian, Xingchen, Wu, Jufang, Li, Hongtao, Wu, Xiaojie, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116427/
https://www.ncbi.nlm.nih.gov/pubmed/33826105
http://dx.doi.org/10.1007/s40121-021-00428-4