Beyond cancer cells: Targeting the tumor microenvironment with gene therapy and armed oncolytic virus

Cancer gene therapies are usually designed either to express wild-type copies of tumor suppressor genes or to exploit tumor-associated phenotypic changes to endow selective cytotoxicity. However, these approaches become less relevant to cancers that contain many independent mutations, and the situat...

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Detalles Bibliográficos
Autores principales: Wan, Peter Kok-Ting, Ryan, Anderson J., Seymour, Leonard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116634/
https://www.ncbi.nlm.nih.gov/pubmed/33845199
http://dx.doi.org/10.1016/j.ymthe.2021.04.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116634/
https://www.ncbi.nlm.nih.gov/pubmed/33845199
http://dx.doi.org/10.1016/j.ymthe.2021.04.015

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