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Terminal Epitope-Dependent Branch Preference of Siglecs Toward N-Glycans

Siglecs are sialic acid–binding immunoglobulin-like lectins that play vital roles in immune cell signaling. Siglecs help the immune system distinguish between self and nonself through the recognition of glycan ligands. While the primary binding specificities of Siglecs are known to be divergent, the...

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Detalles Bibliográficos
Autores principales: Wang, Shuaishuai, Chen, Congcong, Guan, Minhui, Liu, Ding, Wan, Xiu-Feng, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116747/
https://www.ncbi.nlm.nih.gov/pubmed/33996901
http://dx.doi.org/10.3389/fmolb.2021.645999