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An interferon lambda 4-associated variant in the hepatitis C virus RNA polymerase affects viral replication in infected cells

Host IFNL4 haplotype status contributes to the development of chronic hepatitis C virus (HCV) infection in individuals who are acutely infected with the virus. In silico studies revealed that specific amino acid variants at multiple sites on the HCV polyprotein correlate with functional single-nucle...

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Detalles Bibliográficos
Autores principales: Bamford, Connor G.G., McLauchlan, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116938/
https://www.ncbi.nlm.nih.gov/pubmed/32897180
http://dx.doi.org/10.1099/jgv.0.001495