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An interferon lambda 4-associated variant in the hepatitis C virus RNA polymerase affects viral replication in infected cells
Host IFNL4 haplotype status contributes to the development of chronic hepatitis C virus (HCV) infection in individuals who are acutely infected with the virus. In silico studies revealed that specific amino acid variants at multiple sites on the HCV polyprotein correlate with functional single-nucle...
Autores principales: | Bamford, Connor G.G., McLauchlan, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116938/ https://www.ncbi.nlm.nih.gov/pubmed/32897180 http://dx.doi.org/10.1099/jgv.0.001495 |
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