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Andrographolide Induces Noxa-Dependent Apoptosis by Transactivating ATF4 in Human Lung Adenocarcinoma Cells

Lung adenocarcinoma is the most common pathological type of lung cancer with poor patient outcomes; therefore, developing novel therapeutic agents is critically needed. Andrographolide (AD), a major active component derived from the traditional Chinese medicine (TCM) Andrographis paniculate, is a po...

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Detalles Bibliográficos
Autores principales: Zhang, Junqian, Li, Chunjie, Zhang, Li, Heng, Yongqing, Xu, Tong, Zhang, Yunjing, Chen, Xihui, Hoffman, Robert M, Jia, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117100/
https://www.ncbi.nlm.nih.gov/pubmed/33995110
http://dx.doi.org/10.3389/fphar.2021.680589