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Germline risk of clonal haematopoiesis

Clonal haematopoiesis (CH) is a common, age-related expansion of blood cells with somatic mutations that is associated with an increased risk of haematological malignancies, cardiovascular disease and all-cause mortality. CH may be caused by point mutations in genes associated with myeloid neoplasms...

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Detalles Bibliográficos
Autores principales: Silver, Alexander J., Bick, Alexander G., Savona, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117131/
https://www.ncbi.nlm.nih.gov/pubmed/33986496
http://dx.doi.org/10.1038/s41576-021-00356-6