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Aldosterone Is Positively Associated With Circulating FGF23 Levels in Chronic Kidney Disease Across Four Species, and May Drive FGF23 Secretion Directly

BACKGROUND: Chronic kidney disease (CKD) is accompanied by increases in circulating fibroblast growth factor 23 (FGF23) and aldosterone levels. Here, we tested the hypothesis that aldosterone may be one of the driving forces behind increased FGF23 secretion in CKD. METHODS: Using data from a prospec...

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Detalles Bibliográficos
Autores principales: Radloff, Judith, Pagitz, Maximilian, Andrukhova, Olena, Oberbauer, Rainer, Burgener, Iwan A., Erben, Reinhold G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117232/
https://www.ncbi.nlm.nih.gov/pubmed/33995120
http://dx.doi.org/10.3389/fphys.2021.649921