Preparation and quality by design assisted (Qb-d) optimization of bioceramic loaded microspheres for periodontal delivery of doxycycline hyclate

PLGA (Lactic- co-glycolic acid) coated chitosan microspheres loaded with hydroxyapatite and doxycycline hyclate complex were developed in the present study for periodontal delivery. A modified single emulsion method was adopted for the development of microspheres. Formulation was optimized on the ba...

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Detalles Bibliográficos
Autores principales: Jain, Pooja, Garg, Abhinav, Farooq, Uzma, Panda, Amulya K., Mirza, Mohd. Aamir, Noureldeen, Ahmed, Darwish, Hadeer, Iqbal, Zeenat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117247/
https://www.ncbi.nlm.nih.gov/pubmed/34025152
http://dx.doi.org/10.1016/j.sjbs.2021.03.046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117247/
https://www.ncbi.nlm.nih.gov/pubmed/34025152
http://dx.doi.org/10.1016/j.sjbs.2021.03.046

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