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Preparation and quality by design assisted (Qb-d) optimization of bioceramic loaded microspheres for periodontal delivery of doxycycline hyclate

PLGA (Lactic- co-glycolic acid) coated chitosan microspheres loaded with hydroxyapatite and doxycycline hyclate complex were developed in the present study for periodontal delivery. A modified single emulsion method was adopted for the development of microspheres. Formulation was optimized on the ba...

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Detalles Bibliográficos
Autores principales:	Jain, Pooja, Garg, Abhinav, Farooq, Uzma, Panda, Amulya K., Mirza, Mohd. Aamir, Noureldeen, Ahmed, Darwish, Hadeer, Iqbal, Zeenat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117247/ https://www.ncbi.nlm.nih.gov/pubmed/34025152 http://dx.doi.org/10.1016/j.sjbs.2021.03.046

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