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The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

BACKGROUND: Asthma is a heterogeneous chronic inflammatory disease of the airway, involving reversible airflow limitation and airway remodeling. T helper 17 (Th17) cells play an important role in the pathogenesis of allergic asthma. However, there is limited understanding of the signaling pathways c...

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Detalles Bibliográficos
Autores principales: Zhou, Jing, Zhang, Ning, Zhang, Wei, Lu, Caiju, Xu, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117288/
https://www.ncbi.nlm.nih.gov/pubmed/33980319
http://dx.doi.org/10.1186/s13578-021-00560-1