Cargando…
MRI detection of the malignant transformation of stem cells through reporter gene expression driven by a tumor-specific promoter
BACKGROUND: Existing evidence has shown that mesenchymal stem cells (MSCs) can undergo malignant transformation, which is a serious limitation of MSC-based therapies. Therefore, it is necessary to monitor malignant transformation of MSCs via a noninvasive imaging method. Although reporter gene-based...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117323/ https://www.ncbi.nlm.nih.gov/pubmed/33980305 http://dx.doi.org/10.1186/s13287-021-02359-w |