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Vitamin D(3) suppresses intestinal epithelial stemness via ER stress induction in intestinal organoids

BACKGROUND: Vitamin D(3) is important for normal function of the intestinal epithelial cells (IECs). In this study, we aimed to investigate the effects of vitamin D(3) on the differentiation, stemness, and viability of healthy IECs in intestinal organoids. METHODS: Intestinal organoids derived from...

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Detalles Bibliográficos
Autores principales: Sittipo, Panida, Kim, Hyun Kyu, Han, Jaeseok, Lee, Man Ryul, Lee, Yun Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117327/
https://www.ncbi.nlm.nih.gov/pubmed/33985576
http://dx.doi.org/10.1186/s13287-021-02361-2