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P2X7 Receptor–Mediated Inflammation in Cardiovascular Disease

Purinergic P2X7 receptor, a nonselective cation channel, is highly expressed in immune cells as well as cardiac smooth muscle cells and endothelial cells. Its activation exhibits to mediate nucleotide-binding domain (NOD)-like receptor protein 3 (NLRP3) inflammasome activation, resulting in the rele...

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Detalles Bibliográficos
Autores principales: Zhou, Junteng, Zhou, Zhichao, Liu, Xiaojing, Yin, Hai-Yan, Tang, Yong, Cao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117356/
https://www.ncbi.nlm.nih.gov/pubmed/33995071
http://dx.doi.org/10.3389/fphar.2021.654425