Targeting Premature Renal Aging: from Molecular Mechanisms of Cellular Senescence to Senolytic Trials

The biological process of renal aging is characterized by progressive structural and functional deterioration of the kidney leading to end-stage renal disease, requiring renal replacement therapy. Since the discovery of pivotal mechanisms of senescence such as cell cycle arrest, apoptosis inhibition...

Descripción completa

Detalles Bibliográficos
Autores principales: Franzin, Rossana, Stasi, Alessandra, Ranieri, Elena, Netti, Giuseppe Stefano, Cantaluppi, Vincenzo, Gesualdo, Loreto, Stallone, Giovanni, Castellano, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117359/
https://www.ncbi.nlm.nih.gov/pubmed/33995028
http://dx.doi.org/10.3389/fphar.2021.630419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117359/
https://www.ncbi.nlm.nih.gov/pubmed/33995028
http://dx.doi.org/10.3389/fphar.2021.630419

Ejemplares similares