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Targeting Premature Renal Aging: from Molecular Mechanisms of Cellular Senescence to Senolytic Trials
The biological process of renal aging is characterized by progressive structural and functional deterioration of the kidney leading to end-stage renal disease, requiring renal replacement therapy. Since the discovery of pivotal mechanisms of senescence such as cell cycle arrest, apoptosis inhibition...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117359/ https://www.ncbi.nlm.nih.gov/pubmed/33995028 http://dx.doi.org/10.3389/fphar.2021.630419 |