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Quantifying the dynamics of viral recombination during free virus and cell-to-cell transmission in HIV-1 infection

Recombination has been shown to contribute to human immunodeficiency virus-1 (HIV-1) evolution in vivo, but the underlying dynamics are extremely complex, depending on the nature of the fitness landscapes and of epistatic interactions. A less well-studied determinant of recombinant evolution is the...

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Detalles Bibliográficos
Autores principales: Kreger, Jesse, Garcia, Josephine, Zhang, Hongtao, Komarova, Natalia L, Wodarz, Dominik, Levy, David N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117450/
https://www.ncbi.nlm.nih.gov/pubmed/34012557
http://dx.doi.org/10.1093/ve/veab026