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ATF5 and HIF1α cooperatively activate HIF1 signaling pathway in esophageal cancer
BACKGROUND: Esophageal cancer (ESCA) is one of the most common cancers worldwide and has a very poor prognosis. Hypoxia-inducible factor 1 (HIF1) signaling pathway plays a critical role in tumorigenesis and is therefore considered a potential therapeutic target in the treatment of many cancers. Acti...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117505/ https://www.ncbi.nlm.nih.gov/pubmed/33980247 http://dx.doi.org/10.1186/s12964-021-00734-x |