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ATF5 and HIF1α cooperatively activate HIF1 signaling pathway in esophageal cancer

BACKGROUND: Esophageal cancer (ESCA) is one of the most common cancers worldwide and has a very poor prognosis. Hypoxia-inducible factor 1 (HIF1) signaling pathway plays a critical role in tumorigenesis and is therefore considered a potential therapeutic target in the treatment of many cancers. Acti...

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Detalles Bibliográficos
Autores principales: He, Feng, Xiao, Hang, Cai, Yixin, Zhang, Ni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117505/
https://www.ncbi.nlm.nih.gov/pubmed/33980247
http://dx.doi.org/10.1186/s12964-021-00734-x