The culture microenvironment of juvenile idiopathic arthritis synovial fibroblasts is favorable for endochondral bone formation through BMP4 and repressed by chondrocytes

BACKGROUND: We examined influences of conditioned media from chondrocytes (Ch) on juvenile idiopathic arthritis synovial fibroblasts (JFLS) and potential for JFLS to undergo endochondral bone formation (EBF). METHODS: Primary cells from three control fibroblast-like synoviocytes (CFLS) and three JFL...

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Detalles Bibliográficos
Autores principales: Simonds, Megan M., Schlefman, Amanda R., McCahan, Suzanne M., Sullivan, Kathleen E., Rose, Carlos D., Brescia, Anne Marie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117630/
https://www.ncbi.nlm.nih.gov/pubmed/33980237
http://dx.doi.org/10.1186/s12969-021-00556-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117630/
https://www.ncbi.nlm.nih.gov/pubmed/33980237
http://dx.doi.org/10.1186/s12969-021-00556-8

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