Related Factors to Streptococcus pneumoniae Invasive Infection and Clinical Manifestations: The Potential Role of Nasopharyngeal Microbiome
Infections of the lower respiratory tract, such as pneumonia, are one of the leading causes of death worldwide. Streptococcus pneumoniae might colonize the upper respiratory tract and is the main aetiological agent of community-acquired pneumonia (CAP). In the last decades, several factors related t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117960/ https://www.ncbi.nlm.nih.gov/pubmed/33996857 http://dx.doi.org/10.3389/fmed.2021.650271 |
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author | Dietl, Beatriz Henares, Desirée Boix-Palop, Lucía Muñoz-Almagro, Carmen Garau, Javier Calbo, Esther |
author_facet | Dietl, Beatriz Henares, Desirée Boix-Palop, Lucía Muñoz-Almagro, Carmen Garau, Javier Calbo, Esther |
author_sort | Dietl, Beatriz |
collection | PubMed |
description | Infections of the lower respiratory tract, such as pneumonia, are one of the leading causes of death worldwide. Streptococcus pneumoniae might colonize the upper respiratory tract and is the main aetiological agent of community-acquired pneumonia (CAP). In the last decades, several factors related to the host, the microorganism and the antibiotic therapy have been investigated to identify risk factors associated with the development of invasive pneumococcal disease (IPD). Nevertheless, these factors themselves do not explain the risk of developing disease or its severity. Recently, some studies have focused on the importance of nasopharyngeal (NP) microbiome and its relation to respiratory health. This review presents existing evidence of the potential role of NP microbiome in the development of IPD. |
format | Online Article Text |
id | pubmed-8117960 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-81179602021-05-14 Related Factors to Streptococcus pneumoniae Invasive Infection and Clinical Manifestations: The Potential Role of Nasopharyngeal Microbiome Dietl, Beatriz Henares, Desirée Boix-Palop, Lucía Muñoz-Almagro, Carmen Garau, Javier Calbo, Esther Front Med (Lausanne) Medicine Infections of the lower respiratory tract, such as pneumonia, are one of the leading causes of death worldwide. Streptococcus pneumoniae might colonize the upper respiratory tract and is the main aetiological agent of community-acquired pneumonia (CAP). In the last decades, several factors related to the host, the microorganism and the antibiotic therapy have been investigated to identify risk factors associated with the development of invasive pneumococcal disease (IPD). Nevertheless, these factors themselves do not explain the risk of developing disease or its severity. Recently, some studies have focused on the importance of nasopharyngeal (NP) microbiome and its relation to respiratory health. This review presents existing evidence of the potential role of NP microbiome in the development of IPD. Frontiers Media S.A. 2021-04-20 /pmc/articles/PMC8117960/ /pubmed/33996857 http://dx.doi.org/10.3389/fmed.2021.650271 Text en Copyright © 2021 Dietl, Henares, Boix-Palop, Muñoz-Almagro, Garau and Calbo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Dietl, Beatriz Henares, Desirée Boix-Palop, Lucía Muñoz-Almagro, Carmen Garau, Javier Calbo, Esther Related Factors to Streptococcus pneumoniae Invasive Infection and Clinical Manifestations: The Potential Role of Nasopharyngeal Microbiome |
title | Related Factors to Streptococcus pneumoniae Invasive Infection and Clinical Manifestations: The Potential Role of Nasopharyngeal Microbiome |
title_full | Related Factors to Streptococcus pneumoniae Invasive Infection and Clinical Manifestations: The Potential Role of Nasopharyngeal Microbiome |
title_fullStr | Related Factors to Streptococcus pneumoniae Invasive Infection and Clinical Manifestations: The Potential Role of Nasopharyngeal Microbiome |
title_full_unstemmed | Related Factors to Streptococcus pneumoniae Invasive Infection and Clinical Manifestations: The Potential Role of Nasopharyngeal Microbiome |
title_short | Related Factors to Streptococcus pneumoniae Invasive Infection and Clinical Manifestations: The Potential Role of Nasopharyngeal Microbiome |
title_sort | related factors to streptococcus pneumoniae invasive infection and clinical manifestations: the potential role of nasopharyngeal microbiome |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117960/ https://www.ncbi.nlm.nih.gov/pubmed/33996857 http://dx.doi.org/10.3389/fmed.2021.650271 |
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