RACK1 modulates polyglutamine-induced neurodegeneration by promoting ERK degradation in Drosophila

Polyglutamine diseases are neurodegenerative diseases caused by the expansion of polyglutamine (polyQ) tracts within different proteins. Although multiple pathways have been found to modulate aggregation of the expanded polyQ proteins, the mechanisms by which polyQ tracts induced neuronal cell death...

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Detalles Bibliográficos
Autores principales: Xie, Jun, Han, Yongchao, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118270/
https://www.ncbi.nlm.nih.gov/pubmed/33983927
http://dx.doi.org/10.1371/journal.pgen.1009558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118270/
https://www.ncbi.nlm.nih.gov/pubmed/33983927
http://dx.doi.org/10.1371/journal.pgen.1009558

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