Allosteric MAPKAPK2 inhibitors improve plaque stability in advanced atherosclerosis

Atherosclerotic vascular disease resulting from unstable plaques is the leading cause of morbidity and mortality in subjects with type 2 diabetes (T2D), and thus a major therapeutic goal is to discover T2D drugs that can also promote atherosclerotic plaque stability. Genetic or pharmacologic inhibit...

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Detalles Bibliográficos
Autores principales: Ozcan, Lale, Kasikara, Canan, Yurdagul, Arif, Kuriakose, George, Hubbard, Brian, Serrano-Wu, Michael H., Tabas, Ira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118275/
https://www.ncbi.nlm.nih.gov/pubmed/33983975
http://dx.doi.org/10.1371/journal.pone.0246600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118275/
https://www.ncbi.nlm.nih.gov/pubmed/33983975
http://dx.doi.org/10.1371/journal.pone.0246600

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