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Multivariate meta-analysis reveals global transcriptomic signatures underlying distinct human naive-like pluripotent states

The ground or naive pluripotent state of human pluripotent stem cells (hPSCs), which was initially established in mouse embryonic stem cells (mESCs), is an emerging and tentative concept. To verify this vital concept in hPSCs, we performed a multivariate meta-analysis of major hPSC datasets via the...

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Detalles Bibliográficos
Autores principales: Johnson, Kory R., Mallon, Barbara S., Fann, Yang C., Chen, Kevin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118304/
https://www.ncbi.nlm.nih.gov/pubmed/33984026
http://dx.doi.org/10.1371/journal.pone.0251461