Human DICER helicase domain recruits PKR and modulates its antiviral activity

The antiviral innate immune response mainly involves type I interferon (IFN) in mammalian cells. The contribution of the RNA silencing machinery remains to be established, but several recent studies indicate that the ribonuclease DICER can generate viral siRNAs in specific conditions. It has also be...

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Detalles Bibliográficos
Autores principales: Montavon, Thomas C., Baldaccini, Morgane, Lefèvre, Mathieu, Girardi, Erika, Chane-Woon-Ming, Béatrice, Messmer, Mélanie, Hammann, Philippe, Chicher, Johana, Pfeffer, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118307/
https://www.ncbi.nlm.nih.gov/pubmed/33984068
http://dx.doi.org/10.1371/journal.ppat.1009549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118307/
https://www.ncbi.nlm.nih.gov/pubmed/33984068
http://dx.doi.org/10.1371/journal.ppat.1009549

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