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Pbp1, the yeast ortholog of human Ataxin-2, functions in the cell growth on non-fermentable carbon sources
Pbp1, the yeast ortholog of human Ataxin-2, was originally isolated as a poly(A) binding protein (Pab1)-binding protein. Pbp1 regulates the Pan2-Pan3 deadenylase complex, thereby modulating the mRNA stability and translation efficiency. However, the physiological significance of Pbp1 remains unclear...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118320/ https://www.ncbi.nlm.nih.gov/pubmed/33984024 http://dx.doi.org/10.1371/journal.pone.0251456 |