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Abnormally abrupt transitions from sleep-to-wake in Huntington’s disease sheep (Ovis aries) are revealed by automated analysis of sleep/wake transition dynamics

Sleep disturbance is a common and disruptive symptom of neurodegenerative diseases such as Alzheimer’s and Huntington’s disease (HD). In HD patients, sleep fragmentation appears at an early stage of disease, although features of the earliest sleep abnormalities in presymptomatic HD are not fully est...

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Detalles Bibliográficos
Autores principales: Schneider, William T., Vas, Szilvia, Nicol, Alister U., Morton, A. Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118338/
https://www.ncbi.nlm.nih.gov/pubmed/33984047
http://dx.doi.org/10.1371/journal.pone.0251767