In silico design and in vitro expression of novel multiepitope DNA constructs based on HIV-1 proteins and Hsp70 T-cell epitopes

OBJECTIVES: Epitope-driven vaccines carrying highly conserved and immunodominant epitopes have emerged as promising approaches to overcome human immunodeficiency virus-1 (HIV-1) infection. METHODS: Two multiepitope DNA constructs encoding T cell epitopes from HIV-1 Gag, Pol, Env, Nef and Rev protein...

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Detalles Bibliográficos
Autores principales: Akbari, Elahe, Kardani, Kimia, Namvar, Ali, Ajdary, Soheila, Ardakani, Esmat Mirabzadeh, Khalaj, Vahid, Bolhassani, Azam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118377/
https://www.ncbi.nlm.nih.gov/pubmed/33987776
http://dx.doi.org/10.1007/s10529-021-03143-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118377/
https://www.ncbi.nlm.nih.gov/pubmed/33987776
http://dx.doi.org/10.1007/s10529-021-03143-9

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