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The anti-cancer effect of betulinic acid in u937 human leukemia cells is mediated through ROS-dependent cell cycle arrest and apoptosis

Although previous studies have shown anti-cancer activity of betulinic acid (BA), a pentacyclic triterpenoid, against various cancer lines, the underlying molecular mechanisms are not well elucidated. In this study, we evaluated the mechanisms involved in the anti-cancer efficacy of BA in U937 human...

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Detalles Bibliográficos
Autores principales: Park, Cheol, Jeong, Jin-Woo, Han, Min Ho, Lee, Hyesook, Kim, Gi-Young, Jin, Soojung, Park, Jung-Ha, Kwon, Hyun Ju, Kim, Byung Woo, Choi, Yung Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118407/
https://www.ncbi.nlm.nih.gov/pubmed/34234893
http://dx.doi.org/10.1080/19768354.2021.1915380