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Cldn-7 deficiency promotes experimental colitis and associated carcinogenesis by regulating intestinal epithelial integrity

Intestinal epithelial barrier protects intestine from infection and injury, while chronic inflammation is a trigger for tumorigenesis. As a member of tight junctions (TJs) family, Claudin-7 (Cldn-7) is dedicated to maintaining cell polarity and TJs barrier integrity, and closely related to the devel...

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Detalles Bibliográficos
Autores principales: Wang, Kun, Ding, Yuhan, Xu, Chang, Hao, Mengdi, Li, Huimin, Ding, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118418/
https://www.ncbi.nlm.nih.gov/pubmed/34026335
http://dx.doi.org/10.1080/2162402X.2021.1923910