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Longitudinal assessment of B-RAF V595E levels in the peripheral cell-free tumor DNA of a 10-year-old spayed female Korean Jindo dog with unresectable metastatic urethral transitional cell carcinoma for monitoring the treatment response to a RAF inhibitor (sorafenib)

Transitional cell carcinoma (TCC) is the most common malignant tumor of the canine urinary tract. In this case study, a dog with metastatic urethral TCC was treated with sorafenib. The tumor expression levels of receptor tyrosine kinase genes, including VEGFR-1, VEGFR-2, PDGFR-α, PDGFR-β, ALK, EGFR,...

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Detalles Bibliográficos
Autores principales: Kim, Jung-Hyun, Ahn, Dana Hyunjung, Moon, Je-Sung, Han, Hyun-Jung, Bae, Kieun, Yoon, Kyong-Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118428/
https://www.ncbi.nlm.nih.gov/pubmed/33764261
http://dx.doi.org/10.1080/01652176.2021.1905194