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Utility of novel 2-furanones in synthesis of other heterocyclic compounds having anti-inflammatory activity with dual COX2/LOX inhibition

Inflammation is associated with the development of several diseases comprising cancer and cardiovascular disease. Agents that suppress cyclooxygenase (COX) and lipoxygenase (LOX) enzymes, besides chemokines have been suggested to minimise inflammation. Here, a variety of novel heterocyclic and non-h...

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Detalles Bibliográficos
Autores principales: Abd El-Hameed, Rania H., Mahgoub, Shahenda, El-Shanbaky, Hend M., Mohamed, Mosaad S., Ali, Sahar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118430/
https://www.ncbi.nlm.nih.gov/pubmed/33957835
http://dx.doi.org/10.1080/14756366.2021.1908277