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Novel hyaluronic acid oligosaccharide-loaded and CD44v6-targeting oxaliplatin nanoparticles for the treatment of colorectal cancer

Oxaliplatin resistance is one of the main causes of failed colorectal cancer treatment, followed by recurrence and metastasis. In this study, we found that colorectal cancer cells secrete a high level of hyaluronic acid (HA), which interacts with its receptor CD44v6 to mediate colorectal cancer resi...

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Detalles Bibliográficos
Autores principales: Du, Wenlong, Yang, Xiaoping, He, Shenfu, Wang, Jia, Guo, Yuanxian, Kou, Bangguo, Jiang, Yongjie, Bian, Pan, Li, Bingtai, Yin, Lanning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118506/
https://www.ncbi.nlm.nih.gov/pubmed/33974471
http://dx.doi.org/10.1080/10717544.2021.1914777