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Novel hyaluronic acid oligosaccharide-loaded and CD44v6-targeting oxaliplatin nanoparticles for the treatment of colorectal cancer
Oxaliplatin resistance is one of the main causes of failed colorectal cancer treatment, followed by recurrence and metastasis. In this study, we found that colorectal cancer cells secrete a high level of hyaluronic acid (HA), which interacts with its receptor CD44v6 to mediate colorectal cancer resi...
Autores principales: | Du, Wenlong, Yang, Xiaoping, He, Shenfu, Wang, Jia, Guo, Yuanxian, Kou, Bangguo, Jiang, Yongjie, Bian, Pan, Li, Bingtai, Yin, Lanning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118506/ https://www.ncbi.nlm.nih.gov/pubmed/33974471 http://dx.doi.org/10.1080/10717544.2021.1914777 |
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