Hypoxia-inducible factor prolyl hydroxylase inhibitor roxadustat (FG-4592) protects against renal ischemia/reperfusion injury by inhibiting inflammation

Hypoxia-induced inflammation is the critical pathological feature of acute kidney injury (AKI). Activation of hypoxia-inducible factor (HIF) signaling is considered as a central mechanism of body adapting to hypoxia. Hypoxia-inducible factor prolyl hydroxylase inhibitor FG-4592 (Roxadustat) is a fir...

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Detalles Bibliográficos
Autores principales: Miao, A-Feng, Liang, Jian-Xiang, Yao, Lei, Han, Jun-Ling, Zhou, Li-Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Laboratory Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118507/
https://www.ncbi.nlm.nih.gov/pubmed/33966598
http://dx.doi.org/10.1080/0886022X.2021.1915801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118507/
https://www.ncbi.nlm.nih.gov/pubmed/33966598
http://dx.doi.org/10.1080/0886022X.2021.1915801

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