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Small subpopulations of β-cells do not drive islet oscillatory [Ca(2+)] dynamics via gap junction communication

The islets of Langerhans exist as multicellular networks that regulate blood glucose levels. The majority of cells in the islet are excitable, insulin-producing β-cells that are electrically coupled via gap junction channels. β-cells are known to display heterogeneous functionality. However, due to...

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Detalles Bibliográficos
Autores principales: Dwulet, JaeAnn M., Briggs, Jennifer K., Benninger, Richard K. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118513/
https://www.ncbi.nlm.nih.gov/pubmed/33939712
http://dx.doi.org/10.1371/journal.pcbi.1008948