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Small subpopulations of β-cells do not drive islet oscillatory [Ca(2+)] dynamics via gap junction communication
The islets of Langerhans exist as multicellular networks that regulate blood glucose levels. The majority of cells in the islet are excitable, insulin-producing β-cells that are electrically coupled via gap junction channels. β-cells are known to display heterogeneous functionality. However, due to...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118513/ https://www.ncbi.nlm.nih.gov/pubmed/33939712 http://dx.doi.org/10.1371/journal.pcbi.1008948 |