Cargando…

Model guided trait-specific co-expression network estimation as a new perspective for identifying molecular interactions and pathways

A wide variety of 1) parametric regression models and 2) co-expression networks have been developed for finding gene-by-gene interactions underlying complex traits from expression data. While both methodological schemes have their own well-known benefits, little is known about their synergistic pote...

Descripción completa

Detalles Bibliográficos
Autores principales: Kontio, Juho A. J., Pyhäjärvi, Tanja, Sillanpää, Mikko J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118548/
https://www.ncbi.nlm.nih.gov/pubmed/33939702
http://dx.doi.org/10.1371/journal.pcbi.1008960