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Model guided trait-specific co-expression network estimation as a new perspective for identifying molecular interactions and pathways
A wide variety of 1) parametric regression models and 2) co-expression networks have been developed for finding gene-by-gene interactions underlying complex traits from expression data. While both methodological schemes have their own well-known benefits, little is known about their synergistic pote...
Autores principales: | Kontio, Juho A. J., Pyhäjärvi, Tanja, Sillanpää, Mikko J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118548/ https://www.ncbi.nlm.nih.gov/pubmed/33939702 http://dx.doi.org/10.1371/journal.pcbi.1008960 |
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