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3-D Human Renal Tubular Organoids Generated from Urine-Derived Stem Cells for Nephrotoxicity Screening

The development of human cell-based systems to replace the use of rodents or the two-dimensional culture of cells for studying nephrotoxicity is urgently needed. Human urine-derived stem cells were differentiated into renal tubular epithelial cells in three-dimensional (3-D) culture after being indu...

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Detalles Bibliográficos
Autores principales: Guo, Haibin, Deng, Nan, Dou, Lei, Ding, Huifen, Criswell, Tracy, Atala, Anthony, Furdui, Cristina M., Zhang, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118570/
https://www.ncbi.nlm.nih.gov/pubmed/33320634
http://dx.doi.org/10.1021/acsbiomaterials.0c01468