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NSP2 Is Important for Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus to Trigger High Fever-Related COX-2-PGE2 Pathway in Pigs

In 2006, atypical porcine reproductive and respiratory syndrome (PRRS) caused by a highly pathogenic PRRSV (HP-PRRSV) strain broke out in China. Atypical PRRS is characterized by extremely high fever and high mortality in pigs of all ages. Prostaglandin E2 (PGE2) derived from arachidonic acid throug...

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Detalles Bibliográficos
Autores principales: Du, Li, Wang, Honglei, Liu, Fang, Wei, Zeyu, Weng, Changjiang, Tang, Jun, Feng, Wen-hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118602/
https://www.ncbi.nlm.nih.gov/pubmed/33995374
http://dx.doi.org/10.3389/fimmu.2021.657071