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ZNRF1 Mediates Epidermal Growth Factor Receptor Ubiquitination to Control Receptor Lysosomal Trafficking and Degradation

Activation of the epidermal growth factor receptor (EGFR) is crucial for development, tissue homeostasis, and immunity. Dysregulation of EGFR signaling is associated with numerous diseases. EGFR ubiquitination and endosomal trafficking are key events that regulate the termination of EGFR signaling,...

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Detalles Bibliográficos
Autores principales: Shen, Chia-Hsing, Chou, Chih-Chang, Lai, Ting-Yu, Hsu, Jer-En, Lin, You-Sheng, Liu, Huai-Yu, Chen, Yan-Kai, Ho, I-Lin, Hsu, Pang-Hung, Chuang, Tsung-Hsien, Lee, Chih-Yuan, Hsu, Li-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118649/
https://www.ncbi.nlm.nih.gov/pubmed/33996800
http://dx.doi.org/10.3389/fcell.2021.642625