Cargando…
ZNRF1 Mediates Epidermal Growth Factor Receptor Ubiquitination to Control Receptor Lysosomal Trafficking and Degradation
Activation of the epidermal growth factor receptor (EGFR) is crucial for development, tissue homeostasis, and immunity. Dysregulation of EGFR signaling is associated with numerous diseases. EGFR ubiquitination and endosomal trafficking are key events that regulate the termination of EGFR signaling,...
Autores principales: | Shen, Chia-Hsing, Chou, Chih-Chang, Lai, Ting-Yu, Hsu, Jer-En, Lin, You-Sheng, Liu, Huai-Yu, Chen, Yan-Kai, Ho, I-Lin, Hsu, Pang-Hung, Chuang, Tsung-Hsien, Lee, Chih-Yuan, Hsu, Li-Chung |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118649/ https://www.ncbi.nlm.nih.gov/pubmed/33996800 http://dx.doi.org/10.3389/fcell.2021.642625 |
Ejemplares similares
-
The ubiquitin ligase ZNRF1 promotes caveolin-1 ubiquitination and degradation to modulate inflammation
por: Lee, Chih-Yuan, et al.
Publicado: (2017) -
The Src–ZNRF1 axis controls TLR3 trafficking and interferon responses to limit lung barrier damage
por: Lin, You-Sheng, et al.
Publicado: (2023) -
Prognostic value of localization of epidermal growth factor receptor in lung adenocarcinoma
por: Wang, Jinn-Li, et al.
Publicado: (2018) -
Ubiquitination and dynactin regulate TMEPAI lysosomal trafficking
por: Luo, Shenheng, et al.
Publicado: (2017) -
SCF(β-TRCP) E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation
por: Ci, Yanpeng, et al.
Publicado: (2018)