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UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling

To adapt in an ever-changing environment, cells must integrate physical and chemical signals and translate them into biological meaningful information through complex signaling pathways. By combining lipidomic and proteomic approaches with functional analysis, we have shown that ubiquitin domain-con...

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Detalles Bibliográficos
Autores principales: Torrino, Stéphanie, Tiroille, Victor, Dolfi, Bastien, Dufies, Maeva, Hinault, Charlotte, Bonesso, Laurent, Dagnino, Sonia, Uhler, Jennifer, Irondelle, Marie, Gay, Anne-sophie, Fleuriot, Lucile, Debayle, Delphine, Lacas-Gervais, Sandra, Cormont, Mireille, Bertero, Thomas, Bost, Frederic, Gilleron, Jerome, Clavel, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118655/
https://www.ncbi.nlm.nih.gov/pubmed/33884955
http://dx.doi.org/10.7554/eLife.68348