The Downregulation of ADAM17 Exerts Protective Effects against Cardiac Fibrosis by Regulating Endoplasmic Reticulum Stress and Mitophagy

BACKGROUND: A disintegrin and metalloproteinase 17 (ADAM17) is a transmembrane protein that is widely expressed in various tissues; it mediates the shedding of many membrane-bound molecules, involving cell-cell and cell-matrix interactions. We investigated the role of ADAM17 within mouse cardiac fib...

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Detalles Bibliográficos
Autores principales: Guan, Chang, Zhang, Hai-Feng, Wang, Ya-Jing, Chen, Zhi-Teng, Deng, Bing-Qing, Qiu, Qiong, Chen, Si-Xu, Wu, Mao-Xiong, Chen, Yang-Xin, Wang, Jing-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118735/
https://www.ncbi.nlm.nih.gov/pubmed/34035876
http://dx.doi.org/10.1155/2021/5572088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118735/
https://www.ncbi.nlm.nih.gov/pubmed/34035876
http://dx.doi.org/10.1155/2021/5572088

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