Delta-like 4 is required for pulmonary vascular arborization and alveolarization in the developing lung

The molecular mechanisms by which endothelial cells (ECs) regulate pulmonary vascularization and contribute to alveolar epithelial cell development during lung morphogenesis remain unknown. We tested the hypothesis that delta-like 4 (DLL4), an EC Notch ligand, is critical for alveolarization by comb...

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Detalles Bibliográficos
Autores principales: Xia, Sheng, Menden, Heather L., Townley, Nick, Mabry, Sherry M., Johnston, Jeffrey, Nyp, Michael F., Heruth, Daniel P., Korfhagen, Thomas, Sampath, Venkatesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119184/
https://www.ncbi.nlm.nih.gov/pubmed/33830085
http://dx.doi.org/10.1172/jci.insight.134170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119184/
https://www.ncbi.nlm.nih.gov/pubmed/33830085
http://dx.doi.org/10.1172/jci.insight.134170

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